Florfenicol is a derivative of tiamphenicol, in which hydroxil group is substituted by
fluorine atom that induces its antibacterial activity against acetyltransferase bacteria,
sensitive to chloramphenicol. Florfenicol acts bacteriostaticaly on Gram-positive and
Gram-negative bacteria, such as Pasteurllspp., Salmonella spp., Haemophilus spp.,
Proteus spp., Staphylococcus spp., Streptococcus spp., Fusobacterium necroforum,
Mycoplasma spp., Rickettsia spp., Chlamydia and others. Florfenicol inhibits protein
synthesis in bacterial cells.
